Publikationen

2024

Bachmann L, Weber L, Liermann W, Hammon HM, Delling C, Dengler F, Schaufler K, Schwabe M, Eger E, Becker K, Schütz A, Homeier-Bachmann T: Colostrum as a source of ESBL-Escherichia coli in feces of newborn calves. Sci Rep. 2024 Apr 30;14(1):9929. doi: 10.1038/s41598-024-60461-4 

Windhaber C, Heckl A, Csukovich G, Pratscher B, Burgener IA, Biermann N, Dengler F: A matter of differentiation: equine enteroids as a model for the in vivo intestinal epithelium..Vet Res. 2024 Mar 16;55(1):30. doi: 10.1186/s13567-024-01283-0.

Veshkini A, Dengler F, Bachmann L, Liermann W, Helm C, Ulrich R, Delling C, Kühn C, Hammon HM: Cryptosporidium parvum infection alters the intestinal mucosa transcriptome in neonatal calves: implications for immune function. Front Immunol. 2024 Jan 22;15:1351427. doi: 10.3389/fimmu.2024.1351427.

Kather S, Kacza J, Pfannkuche H, Böttcher D, Sung CH, Steiner JM, Gäbel G, Dengler F, Heilmann RM: Expression of the cobalamin transporters cubam and MRP1 in the canine ileum-Upregulation in chronic inflammatory enteropathy .PLoS One. 2024 Jan 11;19(1):e0296024. doi: 10.1371/journal.pone.0296024.

2023

Rietmann SJ, Gäbel G, Dengler F: The intraruminal redox potential is stabilised by opposing influences during fermentation. J Anim Physiol Anim Nutr (Berl). 2023 Jan;107(1):53-61. doi: 10.1111/jpn.13697.

Verhaar N, de Buhr N, von Köckritz-Blickwede M, Dümmer K, Hewicker-Trautwein M, Pfarrer C, Dengler F, Kästner S: Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia. Front Vet Sci. 2023 Feb 24;10:1110019. doi: 10.3389/fvets.2023.1110019.

Dengler F, Domenig O, Kather S, Burgener IA, Steiner JM, Heilmann RM: Dysregulation of intestinal epithelial electrolyte transport in canine chronic inflammatory enteropathy and the role of the renin-angiotensin-aldosterone-system. Front Vet Sci. 2023 Aug 31;10:1217839. doi: 10.3389/fvets.2023.1217839. 

Dengler F, Hammon HM, Liermann W, Görs S, Bachmann L, Helm C, Ulrich R, Delling C: Cryptosporidium parvum competes with the intestinal epithelial cells for glucose and impairs systemic glucose supply in neonatal calves. Vet Res. 2023 May 3;54(1):40. doi: 10.1186/s13567-023-01172-y

Heilmann RM, Csukovich G, Burgener IA, Dengler F: Time to eRAASe chronic inflammation: current advances and future perspectives on renin-angiotensin-aldosterone-system and chronic intestinal inflammation in dogs and humans. Front Vet Sci. 2023 Jun 29;10:1180125. doi: 10.3389/fvets.2023.1180125.

2022

Heilmann RM, Becher A, Dengler F: Electrolyte imbalances in dogs with chronic inflammatory enteropathies.Top Companion Anim Med. 2022 Jan-Feb;46:100597. doi: 10.1016/j.tcam.2021.100597. 

Dengler F, Sternberg F, Grages M, Kästner SB, Verhaar N: Adaptive mechanisms in no flow vs. low flow ischemia in equine jejunum epithelium: Different paths to the same destination..Front Vet Sci. 2022 Sep 8;9:947482. doi: 10.3389/fvets.2022.947482.

2021

Cabrera-García AI, Protschka M, Alber G, Kather S, Dengler F, Müller U, Steiner JM, Heilmann RM: Dysregulation of gastrointestinal RAGE (receptor for advanced glycation end products) expression in dogs with chronic inflammatory enteropathy. Vet Immunol Immunopathol. 2021 Apr;234:110216. doi: 10.1016/j.vetimm.2021.110216.

Dengler F, Kraetzig A, Gäbel G: Butyrate Protects Porcine Colon Epithelium from Hypoxia-Induced Damage on a Functional Level..Nutrients. 2021 Jan 22;13(2):305. doi: 10.3390/nu13020305.

Wanes D, Naim HY, Dengler F: Proliferation and Differentiation of Intestinal Caco-2 Cells Are Maintained in Culture with Human Platelet Lysate Instead of Fetal Calf Serum..Cells. 2021 Nov 5;10(11):3038. doi: 10.3390/cells10113038 .

Dengler F, Sova S, Salo AM, Mäki JM, Koivunen P, Myllyharju J: Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium. Int J Mol Sci. 2021 Apr 14;22(8):4038. doi: 10.3390/ijms22084038.

2020

Kather S, Grützner N, Kook PH, Dengler F, Heilmann RM: Review of cobalamin status and disorders of cobalamin metabolism in dogs. J Vet Intern Med. 2020 Jan;34(1):13-28. doi: 10.1111/jvim.15638. 

Baaske L, Gäbel G, Dengler F: Ruminal epithelium: a checkpoint for cattle health. J Dairy Res. 2020 Aug;87(3):322-329. doi: 10.1017/S0022029920000369.

Dengler F: Activation of AMPK under Hypoxia: Many Roads Leading to Rome. Int J Mol Sci. 2020 Mar 31;21(7):2428. doi: 10.3390/ijms21072428.

Rackwitz R, Dengler F, Gäbel GButyrate Permeation across the Isolated Ovine Reticulum Epithelium. Animals (Basel). 2020 Nov 24;10(12):2198. doi: 10.3390/ani10122198.

Kather S, Sielski L, Dengler F, Jirasek A, Heilmann RM: Prevalence and clinical relevance of hypercobalaminaemia in dogs and cats. Vet J. 2020 Nov;265:105547. doi: 10.1016/j.tvjl.2020.105547.

Laitakari A, Tapio J, Mäkelä KA, Herzig KH, Dengler F, Gylling H, Walkinshaw G, Myllyharju J, Dimova EY, Serpi R, Koivunen P: HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD. J Mol Med (Berl). 2020 May;98(5):719-731. doi: 10.1007/s00109-020-01903-0.

Baaske L, Masur F, Dengler F, Rackwitz R, Kaiser B, Pfannkuche H, Gäbel G: Possible influence of free fatty acid receptors on pH regulation in the ruminal epithelium of sheep.J Anim Physiol Anim Nutr (Berl). 2020 May;104(3):776-789. doi: 10.1111/jpn.13308.

2019

Delling C, Daugschies A, Bangoura B, Dengler F: Cryptosporidium parvum alters glucose transport mechanisms in infected enterocytes. Parasitol Res. 2019 Dec;118(12):3429-3441. doi: 10.1007/s00436-019-06471-y. 

Dengler F, Gäbel G: The Fast Lane of Hypoxic Adaptation: Glucose Transport Is Modulated via A HIF-Hydroxylase-AMPK-Axis in Jejunum Epithelium. Int J Mol Sci. 2019 Oct 9;20(20):4993. doi: 10.3390/ijms20204993.

2017

Dengler F, Rackwitz R, Pfannkuche H, Gäbel G: Glucose transport across lagomorph jejunum epithelium is modulated by AMP-activated protein kinase under hypoxia. J Appl Physiol (1985). 2017 Dec 1;123(6):1487-1500. doi: 10.1152/japplphysiol.00436.2017.

2015

Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G: Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. J Anim Physiol Anim Nutr (Berl). 2015 Apr;99(2):379-90. doi: 10.1111/jpn.12201.

2014

Benesch F, Dengler F, Masur F, Pfannkuche H, Gäbel G: Monocarboxylate transporters 1 and 4: expression and regulation by PPARα in ovine ruminal epithelial cells. Am J Physiol Regul Integr Comp Physiol. 2014 Dec 15;307(12):R1428-37. doi: 10.1152/ajpregu.00408.2013.

Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G: Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. Acta Physiol (Oxf). 2014 Feb;210(2):403-14. doi: 10.1111/apha.12155.