Publikationen

Sener-Aydemir A, Dengler F, Larsberg F, Rivera-Chacon R, Castillo-Lopez E, Zebeli Q, Kreuzer-Redmer S: Site matters: differences in gene expression profile along the bovine rumen papilla during subacute rumen acidosis. Int. J. Mol. Sci. 2024, 25(22), 12303. doi: 10.3390/ijms252212303.

Kunath T, Kather S, Dengler F, Nexo E, Pfannkuche H, Heilmann RM: Serum transcobalamin concentration in cats – method validation and evaluation in chronic enteropathies and other conditions. VetSci 2024.

Bachmann L, Weber L, Liermann W, Hammon HM, Delling C, Dengler F, Schaufler K, Schwabe M, Eger E, Becker K, Schütz A, Homeier-Bachmann T: Colostrum as a source of ESBL-Escherichia coli in feces of newborn calves. Sci Rep. 2024 Apr 30;14(1):9929. doi: 10.1038/s41598-024-60461-4 

Windhaber C, Heckl A, Csukovich G, Pratscher B, Burgener IA, Biermann N, Dengler F: A matter of differentiation: equine enteroids as a model for the in vivo intestinal epithelium. Vet Res. 2024 Mar 16;55(1):30. doi: 10.1186/s13567-024-01283-0.

Veshkini A, Dengler F, Bachmann L, Liermann W, Helm C, Ulrich R, Delling C, Kühn C, Hammon HM: Cryptosporidium parvum infection alters the intestinal mucosa transcriptome in neonatal calves: implications for immune function. Front Immunol. 2024 Jan 22;15:1351427. doi: 10.3389/fimmu.2024.1351427.

Kather S, Kacza J, Pfannkuche H, Böttcher D, Sung CH, Steiner JM, Gäbel G, Dengler F, Heilmann RM: Expression of the cobalamin transporters cubam and MRP1 in the canine ileum-Upregulation in chronic inflammatory enteropathy .PLoS One. 2024 Jan 11;19(1):e0296024. doi: 10.1371/journal.pone.0296024.

Rietmann SJ, Gäbel G, Dengler F: The intraruminal redox potential is stabilised by opposing influences during fermentation. J Anim Physiol Anim Nutr (Berl). 2023 Jan;107(1):53-61. doi: 10.1111/jpn.13697.

Verhaar N, de Buhr N, von Köckritz-Blickwede M, Dümmer K, Hewicker-Trautwein M, Pfarrer C, Dengler F, Kästner S: Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia. Front Vet Sci. 2023 Feb 24;10:1110019. doi: 10.3389/fvets.2023.1110019.

Dengler F, Domenig O, Kather S, Burgener IA, Steiner JM, Heilmann RM: Dysregulation of intestinal epithelial electrolyte transport in canine chronic inflammatory enteropathy and the role of the renin-angiotensin-aldosterone-system. Front Vet Sci. 2023 Aug 31;10:1217839. doi: 10.3389/fvets.2023.1217839. 

Dengler F, Hammon HM, Liermann W, Görs S, Bachmann L, Helm C, Ulrich R, Delling C: Cryptosporidium parvum competes with the intestinal epithelial cells for glucose and impairs systemic glucose supply in neonatal calves. Vet Res. 2023 May 3;54(1):40. doi: 10.1186/s13567-023-01172-y

Heilmann RM, Csukovich G, Burgener IA, Dengler F: Time to eRAASe chronic inflammation: current advances and future perspectives on renin-angiotensin-aldosterone-system and chronic intestinal inflammation in dogs and humans. Front Vet Sci. 2023 Jun 29;10:1180125. doi: 10.3389/fvets.2023.1180125.

Heilmann RM, Becher A, Dengler F: Electrolyte imbalances in dogs with chronic inflammatory enteropathies.Top Companion Anim Med. 2022 Jan-Feb;46:100597. doi: 10.1016/j.tcam.2021.100597. 

Dengler F, Sternberg F, Grages M, Kästner SB, Verhaar N: Adaptive mechanisms in no flow vs. low flow ischemia in equine jejunum epithelium: Different paths to the same destination..Front Vet Sci. 2022 Sep 8;9:947482. doi: 10.3389/fvets.2022.947482.

Cabrera-García AI, Protschka M, Alber G, Kather S, Dengler F, Müller U, Steiner JM, Heilmann RM: Dysregulation of gastrointestinal RAGE (receptor for advanced glycation end products) expression in dogs with chronic inflammatory enteropathy. Vet Immunol Immunopathol. 2021 Apr;234:110216. doi: 10.1016/j.vetimm.2021.110216.

Dengler F, Kraetzig A, Gäbel G: Butyrate Protects Porcine Colon Epithelium from Hypoxia-Induced Damage on a Functional Level..Nutrients. 2021 Jan 22;13(2):305. doi: 10.3390/nu13020305.

Wanes D, Naim HY, Dengler F: Proliferation and Differentiation of Intestinal Caco-2 Cells Are Maintained in Culture with Human Platelet Lysate Instead of Fetal Calf Serum..Cells. 2021 Nov 5;10(11):3038. doi: 10.3390/cells10113038 .

Dengler F, Sova S, Salo AM, Mäki JM, Koivunen P, Myllyharju J: Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium. Int J Mol Sci. 2021 Apr 14;22(8):4038. doi: 10.3390/ijms22084038.

Kather S, Grützner N, Kook PH, Dengler F, Heilmann RM: Review of cobalamin status and disorders of cobalamin metabolism in dogs. J Vet Intern Med. 2020 Jan;34(1):13-28. doi: 10.1111/jvim.15638. 

Baaske L, Gäbel G, Dengler F: Ruminal epithelium: a checkpoint for cattle health. J Dairy Res. 2020 Aug;87(3):322-329. doi: 10.1017/S0022029920000369.

Dengler F: Activation of AMPK under Hypoxia: Many Roads Leading to Rome. Int J Mol Sci. 2020 Mar 31;21(7):2428. doi: 10.3390/ijms21072428.

Rackwitz R, Dengler F, Gäbel GButyrate Permeation across the Isolated Ovine Reticulum Epithelium. Animals (Basel). 2020 Nov 24;10(12):2198. doi: 10.3390/ani10122198.

Kather S, Sielski L, Dengler F, Jirasek A, Heilmann RM: Prevalence and clinical relevance of hypercobalaminaemia in dogs and cats. Vet J. 2020 Nov;265:105547. doi: 10.1016/j.tvjl.2020.105547.

Laitakari A, Tapio J, Mäkelä KA, Herzig KH, Dengler F, Gylling H, Walkinshaw G, Myllyharju J, Dimova EY, Serpi R, Koivunen P: HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD. J Mol Med (Berl). 2020 May;98(5):719-731. doi: 10.1007/s00109-020-01903-0.

Baaske L, Masur F, Dengler F, Rackwitz R, Kaiser B, Pfannkuche H, Gäbel G: Possible influence of free fatty acid receptors on pH regulation in the ruminal epithelium of sheep.J Anim Physiol Anim Nutr (Berl). 2020 May;104(3):776-789. doi: 10.1111/jpn.13308.

Delling C, Daugschies A, Bangoura B, Dengler F: Cryptosporidium parvum alters glucose transport mechanisms in infected enterocytes. Parasitol Res. 2019 Dec;118(12):3429-3441. doi: 10.1007/s00436-019-06471-y. 

Dengler F, Gäbel G: The Fast Lane of Hypoxic Adaptation: Glucose Transport Is Modulated via A HIF-Hydroxylase-AMPK-Axis in Jejunum Epithelium. Int J Mol Sci. 2019 Oct 9;20(20):4993. doi: 10.3390/ijms20204993.

Dengler F, Rackwitz R, Pfannkuche H, Gäbel G: Glucose transport across lagomorph jejunum epithelium is modulated by AMP-activated protein kinase under hypoxia. J Appl Physiol (1985). 2017 Dec 1;123(6):1487-1500. doi: 10.1152/japplphysiol.00436.2017.

Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G: Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. J Anim Physiol Anim Nutr (Berl). 2015 Apr;99(2):379-90. doi: 10.1111/jpn.12201.

Benesch F, Dengler F, Masur F, Pfannkuche H, Gäbel G: Monocarboxylate transporters 1 and 4: expression and regulation by PPARα in ovine ruminal epithelial cells. Am J Physiol Regul Integr Comp Physiol. 2014 Dec 15;307(12):R1428-37. doi: 10.1152/ajpregu.00408.2013.

Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G: Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. Acta Physiol (Oxf). 2014 Feb;210(2):403-14. doi: 10.1111/apha.12155.